A centrality based multi-objective approach to disease gene association.
Tyler Kennedy CollinsSheridan K. HoughtenPublished in: Biosyst. (2020)
Keyphrases
- multi objective
- complex diseases
- gene gene
- microarray
- disease genes
- gene networks
- gene gene interactions
- linkage disequilibrium
- evolutionary algorithm
- multi objective optimization
- optimization algorithm
- social network analysis
- single nucleotide polymorphisms
- gene function
- candidate genes
- genetic algorithm
- gene expression
- protein protein interaction networks
- multiple objectives
- gene expression data
- genome wide association studies
- genome wide
- nsga ii
- bi objective
- particle swarm optimization
- network analysis
- objective function
- microarray data
- biomedical literature
- disease diagnosis
- multi objective optimization problems
- social networks
- conflicting objectives
- high throughput
- gene sets
- gene ontology
- pareto optimal
- biological entities
- dna microarray
- related genes
- optimum design
- molecular level
- biological data
- multi objective evolutionary
- differentially expressed genes
- optimization problems
- trade off