A regulatory similarity measure using the location information of transcription factor binding sites in Saccharomyces cerevisiae.
Wei-Sheng WuMing-Liang WeiChia-Ming YehDarby Tien-Hao ChangPublished in: BMC Syst. Biol. (2014)
Keyphrases
- location information
- transcription factors
- saccharomyces cerevisiae
- similarity measure
- transcription factor binding sites
- binding sites
- microarray
- gene expression
- component analysis
- genome wide
- gene regulation
- dna sequences
- regulatory networks
- computational biology
- systems biology
- co occurrence
- biomedical literature
- regulatory elements
- high throughput
- dna binding
- genomic data
- biological processes
- highly correlated
- motif discovery
- sequence data
- statistical tests
- pairwise
- gene expression data
- microarray data
- statistical significance
- semantic similarity
- clustering method
- signaling pathways
- data collection
- databases