Maximum Sequence Alignment Fails to Predict Off-targeted Gene Regulation by RNAi.
Amanda BirminghamEmily M. AndersonWilliam S. MarshallAnastasia KhvorovaPublished in: CSB Workshops (2005)
Keyphrases
- sequence alignment
- gene regulation
- binding sites
- gene expression
- transcription factors
- gene expression data
- genome wide
- pairwise
- systems biology
- gene regulatory networks
- microarray
- dynamic programming
- biological systems
- protein sequences
- microarray data
- regulatory networks
- genome sequences
- data sets
- amino acids
- sequence data
- dna sequences
- high throughput
- dimensionality reduction
- sequence databases
- genomic sequences
- comparative genomics
- biological networks
- statistical significance
- computational methods
- co occurrence
- data mining