A Hierarchical Parallel Scheme for Global Parameter Estimation in Systems Biology.
Jian HeMasha SosonkinaClifford A. ShafferJohn J. TysonLayne T. WatsonJason W. ZwolakPublished in: IPDPS (2004)
Keyphrases
- statistical methods
- parameter estimation
- biological data
- systems biology
- statistical models
- maximum likelihood
- biological networks
- high throughput
- molecular biology
- least squares
- model selection
- em algorithm
- gene regulatory networks
- maximum likelihood estimation
- markov random field
- expectation maximization
- approximate inference
- protein protein interactions
- parameter estimation algorithm
- biological systems
- structure learning
- data mining
- microarray
- complex systems
- computational biology