Physical modeling of ribosomes along messenger RNA: Estimating kinetic parameters from ribosome profiling experiments using a ballistic model.
Carole ChevalierJérôme DorignacYahaya IbrahimArmelle ChoquetAlexandre DavidJulie RipollEric RivalsFrédéric GenietNils-Ole WalliserJohn PalmeriAndrea ParmeggianiJean-Charles WalterPublished in: PLoS Comput. Biol. (2023)
Keyphrases
- probabilistic model
- computational model
- parameter values
- mathematical model
- modeling framework
- physical models
- high level
- sensitivity analysis
- closed form
- experimental data
- statistical model
- similarity measure
- real world
- theoretical framework
- parameter estimation
- management system
- parameter space
- simulation model
- prediction model
- hidden markov models
- metamodel
- parametric models
- maximum likelihood estimation
- measured data
- physical laws