Computational Analysis of Activation of Dimerized Epidermal Growth Factor Receptor Kinase Using the String Method and Markov State Model.
Masao InoueToru EkimotoTsutomu YamaneMitsunori IkeguchiPublished in: J. Chem. Inf. Model. (2024)
Keyphrases
- markov model
- modeling method
- prior knowledge
- cost function
- theoretical analysis
- probabilistic model
- statistical model
- growth model
- mathematical model
- parameter estimation
- objective function
- linear model
- prediction model
- detection method
- optimization method
- high order
- prior information
- gaussian distribution
- classification method
- support vector machine
- input data
- network model
- evaluation method
- bayesian framework
- em algorithm
- linear regression
- test data
- similarity measure
- regression analysis
- bp neural network
- computational models
- energy function
- sensitivity analysis
- statistical methods
- classification algorithm
- clustering method
- closed form
- reconstruction method
- pairwise
- genetic algorithm