Evidence that microRNA precursors, unlike other non-coding RNAs, have lower folding free energies than random sequences.
Eric BonnetJan WuytsPierre RouzéYves Van de PeerPublished in: Bioinform. (2004)
Keyphrases
- secondary structure
- rna sequences
- protein folding
- coding regions
- amino acid sequences
- multiple alignment
- multiple sequence alignment
- rna secondary structures
- sequence similarity
- coding scheme
- protein sequences
- sequence alignment
- computational methods
- pseudorandom
- graph cuts
- markov random field
- binding sites
- genome sequences
- hidden markov models
- sequential patterns
- coding method
- higher order
- protein structure prediction
- structural features
- human genome
- image sequences
- protein structure
- gene regulation
- energy minimization
- energy function
- computational complexity