Improved human disease candidate gene prioritization using mouse phenotype.
Jing ChenHuan XuBruce J. AronowAnil G. JeggaPublished in: BMC Bioinform. (2007)
Keyphrases
- single nucleotide polymorphisms
- gene expression
- genome wide
- disease genes
- high throughput
- genetic variation
- genotype phenotype
- complex diseases
- gene function
- human genome
- microarray
- functional genomics
- computational approaches
- statistical methods
- biologically meaningful
- gene expression data
- related genes
- user interface
- protein interaction
- differential expression
- association studies
- dna sequences
- highly correlated
- clinically relevant
- sequence data
- human subjects
- protein protein interaction networks
- candidate genes
- genomic data
- gene ontology