Grid-based stochastic search for hierarchical gene-gene interactions in population-based genetic studies of common human diseases.
Jason H. MoorePeter C. AndrewsRandal S. OlsonSarah E. CarlsonCurt LarockMario J. BulhoesJames P. O'ConnorEllen M. GreytakSteven ArmentroutPublished in: BioData Min. (2017)
Keyphrases
- stochastic search
- gene gene interactions
- single nucleotide polymorphisms
- complex diseases
- variable selection
- genome wide association studies
- genetic variation
- simulated annealing
- genome wide
- grammatical evolution
- high throughput
- human genome
- consistency checking
- computational approaches
- sequence data
- decision trees
- biological data
- dna sequences
- search methods
- related genes
- cross validation
- metaheuristic
- dimension reduction
- high dimensional
- highly correlated
- combinatorial optimization
- tree search
- data mining
- statistical methods
- unsupervised learning
- particle swarm optimization
- risk factors
- statistical tests
- search tree
- genomic data
- genetic programming
- k means
- search algorithm
- support vector
- machine learning
- databases