AREM: Aligning Short Reads from ChIP-Sequencing by Expectation Maximization.
Daniel NewkirkJacob BiesingerAlvin ChonKyoko YokomoriXiaohui XiePublished in: J. Comput. Biol. (2011)
Keyphrases
- expectation maximization
- em algorithm
- low cost
- high speed
- generative model
- maximum likelihood
- high density
- gaussian mixture model
- probabilistic model
- analog vlsi
- unsupervised learning
- mixture model
- parameter estimation
- reference genome
- maximum likelihood estimation
- gaussian mixture
- maximum a posteriori
- high throughput sequencing
- bayesian framework
- real time
- single chip
- programmable logic
- image registration
- image segmentation