A Bayesian statistical approach of improving knowledge-based scoring functions for protein-ligand interactions.
Sam Z. GrinterXiaoqin ZouPublished in: J. Comput. Chem. (2014)
Keyphrases
- scoring functions
- protein protein
- scoring function
- virtual screening
- protein protein interactions
- drug design
- protein sequences
- computational methods
- interaction networks
- high throughput
- protein interaction
- bayesian networks
- protein structure
- drug discovery
- similarity measure
- statistical methods
- structure learning
- protein structure prediction
- protein function
- maximum likelihood
- protein interaction networks