Reliable protein structure refinement using a physical energy function.
Matthew S. LinTeresa Head-GordonPublished in: J. Comput. Chem. (2011)
Keyphrases
- energy function
- protein structure
- energy minimization
- graph cuts
- markov random field
- molecular biology
- protein sequences
- global minimum
- active contours
- shape model
- hopfield neural network
- image segmentation
- secondary structure
- level set
- protein tertiary structure
- amino acids
- segmentation method
- amino acid sequences
- belief propagation
- protein function
- protein structure prediction
- energy functional
- nuclear magnetic resonance
- problems in computer vision
- machine learning
- protein structure alignment
- smoothness constraint
- computer vision
- reconstruction process
- maximum a posteriori
- image processing
- high throughput