Prospective virtual screening for novel p53-MDM2 inhibitors using ultrafast shape recognition.
Sachin P. PatilPedro J. BallesterCassidy R. KerezsiPublished in: J. Comput. Aided Mol. Des. (2014)
Keyphrases
- shape recognition
- virtual screening
- drug discovery
- similarity searching
- high throughput
- shape analysis
- binding sites
- fourier descriptors
- dissimilarity measure
- scoring function
- protein protein interactions
- object recognition
- string matching
- early stage
- metric space
- image processing
- database
- systems biology
- pattern recognition
- machine learning
- pairwise
- feature selection
- pattern matching
- image retrieval