Unsupervised protein embeddings outperform hand-crafted sequence and structure features at predicting molecular function.
Amelia Villegas-MorcilloStavros MakrodimitrisRoeland C. H. J. van HamAngel M. GomezVictoria E. SánchezMarcel J. T. ReindersPublished in: Bioinform. (2021)
Keyphrases
- hand crafted
- molecular structures
- structural information
- feature extraction
- structural features
- linguistic features
- feature set
- semi supervised
- supervised learning
- dimensionality reduction
- unsupervised learning
- feature space
- probabilistic model
- classification accuracy
- information extraction
- domain independent
- vector space
- prior knowledge
- protein protein interactions
- learning algorithm