Bioactive Conformations of Small Peptides: A Method for Selection of Candidates Based on Conformations of Active and Inactive Analogs and Its Application to Muramyl Dipeptide.
Primoz PristovsekJurka KidricDusan HadziPublished in: J. Chem. Inf. Comput. Sci. (1995)
Keyphrases
- high accuracy
- experimental evaluation
- high precision
- computational complexity
- significant improvement
- clustering method
- detection method
- synthetic data
- computational cost
- fine tuning
- similarity measure
- protein structure
- pattern classification
- segmentation method
- fine grained
- support vector machine svm
- dynamic programming
- cost function
- evolutionary algorithm