Self-supervised Pocket Pretraining via Protein Fragment-Surroundings Alignment.
Bowen GaoYinjun JiaYuanle MoYuyan NiWei-Ying MaZhi-Ming MaYanyan LanPublished in: ICLR (2024)
Keyphrases
- sequence alignment
- multiple sequence alignment
- protein structure alignment
- protein sequences
- remote homology detection
- protein structure
- multiple sequence alignments
- multiple alignment
- amino acids
- image alignment
- protein structure prediction
- proteomic data
- dynamic time warping
- search algorithm
- protein interaction data
- protein folding
- contact map
- subcellular localization
- genetic algorithm
- memory efficient
- protein protein interactions
- pairwise
- drug design
- protein function
- drug discovery
- binding sites
- tandem mass spectra
- similarity measure