Pharmacophore Knowledge Refinement Method in the Chemical Structure Space.
Satoshi FujishimaYoshimasa TakahashiTakashi OkadaPublished in: Discovery Science (2007)
Keyphrases
- significant improvement
- experimental evaluation
- pairwise
- knowledge base
- computational cost
- domain knowledge
- prior knowledge
- neural network
- human knowledge
- high precision
- tree structure
- clustering method
- high accuracy
- support vector machine svm
- edge detection
- segmentation method
- detection method
- medical images
- search space
- classification accuracy
- similarity measure
- video sequences
- computational complexity
- artificial neural networks
- evolutionary algorithm