LeafCutterMD: an algorithm for outlier splicing detection in rare diseases.
W. Garrett JenkinsonYang I LiShubham BasuMargot A. CousinGavin R. OliverEric W. KleePublished in: Bioinform. (2020)
Keyphrases
- detection algorithm
- computational complexity
- high accuracy
- preprocessing
- dynamic programming
- cost function
- times faster
- computational cost
- experimental evaluation
- np hard
- detection accuracy
- segmentation algorithm
- k means
- significant improvement
- search space
- optimal solution
- learning algorithm
- probabilistic model
- worst case
- objective function
- linear programming
- computationally efficient
- intrusion detection
- bayesian networks
- image segmentation
- detection method
- improved algorithm
- genetic algorithm