A Two-Phase Improved Correlation Method for Automatic Particle Selection in Cryo-EM.
Fa ZhangYu ChenFei RenXuan WangZhiyong LiuXiaohua WanPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2017)
Keyphrases
- fully automatic
- significant improvement
- high accuracy
- detection method
- high precision
- clustering method
- em algorithm
- improved algorithm
- preprocessing
- pairwise
- decision trees
- synthetic data
- correlation coefficient
- gaussian distribution
- segmentation method
- selection strategy
- support vector machine svm
- optimization algorithm
- parameter estimation
- computationally efficient
- simulated annealing
- computational cost
- experimental evaluation
- dynamic programming
- prior knowledge
- image sequences