In silico deleterious prediction of nonsynonymous single nucleotide polymorphisms in Neurexin1 gene for mental disorders.
Ashraf HendamAhmed Farouk Al-SadekHesham Ahmed HefnyPublished in: Int. J. Bioinform. Res. Appl. (2020)
Keyphrases
- single nucleotide polymorphisms
- high throughput
- complex diseases
- genome wide
- computational approaches
- gene regulatory networks
- human genome
- microarray
- gene expression
- linkage disequilibrium
- dna sequences
- biological data
- low cost
- gene sets
- genomic data
- statistical methods
- highly correlated
- variable selection
- systems biology
- statistical tests
- microarray data
- high dimensionality
- sample size
- association studies
- dimensionality reduction