Estimating the parameters of multi-state models with time-dependent covariates through likelihood decomposition.
Emmanuelle DantonyM.-H. ElsensohnAntoine DanyE. VillarC. CouchoudRené ÉcochardPublished in: Comput. Biol. Medicine (2016)
Keyphrases
- parameter estimation
- parametric models
- hidden markov models
- probabilistic model
- maximum likelihood
- ordinary differential equations
- free parameters
- update equations
- hidden states
- prior knowledge
- state space
- statistical models
- experimental data
- analytical models
- decomposition algorithm
- likelihood function
- state variables
- linear model
- computational models
- machine learning
- model selection
- expectation maximization
- control system
- artificial neural networks
- image segmentation