ALCHEMY: a reliable method for automated SNP genotype calling for small batch sizes and highly homozygous populations.
Mark H. WrightChih-Wei TungKeyan ZhaoAndy ReynoldsSusan McCouchCarlos D. BustamantePublished in: Bioinform. (2010)
Keyphrases
- detection method
- cost function
- objective function
- computational complexity
- significant improvement
- high precision
- segmentation method
- pairwise
- preprocessing
- similarity measure
- neural network
- data sets
- high accuracy
- fully automatic
- machine learning
- synthetic data
- machine learning methods
- statistical methods
- classification method
- feature set
- denoising