Parameter estimation in large-scale systems biology models: a parallel and self-adaptive cooperative strategy.
David R. PenasPatricia GonzálezJose A. EgeaRamón DoalloJulio R. BangaPublished in: BMC Bioinform. (2017)
Keyphrases
- parameter estimation
- cooperative
- statistical models
- model selection
- systems biology
- markov random field
- maximum likelihood
- em algorithm
- least squares
- expectation maximization
- parameter estimation algorithm
- biochemical networks
- high throughput
- approximate inference
- probabilistic model
- pairwise
- maximum likelihood estimation
- parameter estimates
- biological systems
- structure learning
- gene expression data
- computational biology
- gene regulatory networks
- image sequences
- feature selection
- computer vision