Identification of Small-Molecule Inhibitors of Fibroblast Growth Factor 23 Signaling via In Silico Hot Spot Prediction and Molecular Docking to α-Klotho.
Shih-Hsien LiuZhousheng XiaoSambit K. MishraJulie C. MitchellJeremy C. SmithL. Darryl QuarlesLoukas PetridisPublished in: J. Chem. Inf. Model. (2022)
Keyphrases
- hot spots
- hiv protease
- protein protein interactions
- wet lab
- coarse grained
- location prediction
- biological data
- drug discovery
- human immunodeficiency virus
- high throughput
- prediction accuracy
- drug design
- fine grained
- sequence analysis
- three dimensional
- spatial analysis
- computational methods
- network analysis
- graph theory
- linear support vector machines
- point processes