Derived SNP Alleles are Used More Frequently than Ancestral Alleles as Risk-associated Variants in Common Human Diseases.
Olga Y. GorlovaJun YingChristopher I. AmosMargaret R. SpitzBo PengIvan P. GorlovPublished in: J. Bioinform. Comput. Biol. (2012)
Keyphrases
- single nucleotide polymorphisms
- genetic variation
- sequence data
- genome wide
- high throughput
- computational approaches
- dna sequences
- human genome
- complex diseases
- variable selection
- highly correlated
- statistical methods
- association studies
- genome wide association studies
- risk management
- risk factors
- statistical tests
- linkage disequilibrium
- high risk
- closely related
- biological data
- copy number
- computational methods
- decision support system
- decision making
- neural network