Binding Free Energy Calculation via Molecular Dynamics Simulations for a miRNA: mRNA Interaction.
Giulia PacielloAndrea AcquavivaElisa FicarraM. A. DeriuA. GrossoEnrico MaciiPublished in: BIOINFORMATICS (2011)
Keyphrases
- computational biology
- regulatory networks
- free energy
- transcription factors
- molecular dynamics simulations
- genome wide
- post transcriptional
- machine learning
- fixed point
- competitive learning
- belief propagation
- gene regulation
- approximate inference
- upper bound
- molecular dynamics
- posterior distribution
- systems biology
- gene function
- high throughput
- gene regulatory networks
- lower bound
- binding sites
- computational methods
- bayesian framework
- active learning
- feature selection
- microarray