Rainer Merkl

Publication Activity (10 Years)

Years Active: 2003-2021
Publications (10 Years): 4

Top Topics

Neighborhood Information

Computational Approaches

Top Venues

PLoS Comput. Biol.

Publications

Samuel Schmitz, Moritz Ertelt, Rainer Merkl, Jens Meiler
Rosetta design with co-evolutionary information retains protein function. PLoS Comput. Biol. 17 (1) (2021)
Robert Esch, Rainer Merkl
Conserved genomic neighborhood is a strong but no perfect indicator for a direct interaction of microbial gene products. BMC Bioinform. 21 (1) (2020)
Patrick Löffler, Samuel Schmitz, Enrico Hupfeld, Reinhard Sterner, Rainer Merkl
Rosetta: MSF: a modular framework for multi-state computational protein design. PLoS Comput. Biol. 13 (6) (2017)
Florian Kandlinger, Maximilian G. Plach, Rainer Merkl
AGeNNT: annotation of enzyme families by means of refined neighborhood networks. BMC Bioinform. 18 (1) (2017)
Clemens Zvácek, Gerald Friedrichs, Leonhard Heizinger, Rainer Merkl
An assessment of catalytic residue 3D ensembles for the prediction of enzyme function. BMC Bioinform. 16 (2015)
Jan-Oliver Janda, Ajmal Popal, Jochen Bauer, Markus Busch, Michael Klocke, Wolfgang Spitzer, Jörg Keller, Rainer Merkl
H2rs: Deducing evolutionary and functionally important residue positions by means of an entropy and similarity based analysis of multiple sequence alignments. BMC Bioinform. 15 (2014)
Jan-Oliver Janda, Andreas Meier, Rainer Merkl
CLIPS-4D: a classifier that distinguishes structurally and functionally important residue-positions based on sequence and 3D data. Bioinform. 29 (23) (2013)
Jan-Oliver Janda, Markus Busch, Fabian Kück, Mikhail Porfenenko, Rainer Merkl
CLIPS-1D: analysis of multiple sequence alignments to deduce for residue-positions a role in catalysis, ligand-binding, or protein structure. BMC Bioinform. 13 (2012)
Andreas Pürzer, Felix Grassmann, Dietmar Birzer, Rainer Merkl
Key2Ann: a tool to process sequence sets by replacing database identifiers with a human-readable annotation. J. Integr. Bioinform. 8 (1) (2011)
Florian Fink, Jochen Hochrein, Vincent Wolowski, Rainer Merkl, Wolfram Gronwald
PROCOS: Computational analysis of protein-protein complexes. J. Comput. Chem. 32 (12) (2011)
André Fischer, Nils Enkler, Gerd Neudert, Marco Bocola, Reinhard Sterner, Rainer Merkl
TransCent: Computational enzyme design by transferring active sites and considering constraints relevant for catalysis. BMC Bioinform. 10 (2009)
Rainer Merkl, Matthias Zwick
: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments. BMC Bioinform. 9 (2008)
Rainer Merkl
AMIGOS: A Method for the Inspection of Genomic Organisation or Structure and its Application to Characterise Conserved Gene Arrangements. Silico Biol. 6 (4) (2006)
Stephan Waack, Oliver Keller, Roman Asper, Thomas Brodag, Carsten Damm, Wolfgang Florian Fricke, Katharina Surovcik, Peter Meinicke, Rainer Merkl
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models. BMC Bioinform. 7 (2006)
Peter Meinicke, Maike Tech, Burkhard Morgenstern, Rainer Merkl
Oligo kernels for datamining on biological sequences: a case study on prokaryotic translation initiation sites. BMC Bioinform. 5 (2004)
Rainer Merkl
SIGI: score-based identification of genomic islands. BMC Bioinform. 5 (2004)
Arnim Wiezer, Rainer Merkl
secureBLAST. Silico Biol. 3 (4) (2003)
Maike Tech, Rainer Merkl
YACOP: Enhanced gene prediction obtained by a combination of existing methods. Silico Biol. 3 (4) (2003)