Guy N. Brock

Publication Activity (10 Years)

Years Active: 2008-2021
Publications (10 Years): 12

Top Topics

Differentially Expressed

Nearest Neighbor

Differential Expression

Top Venues

Model. Assist. Stat. Appl.

BMC Medical Informatics Decis. Mak.

Source Code Biol. Medicine

Publications

Caitlin E. Coombes, Xin Liu, Zachary B. Abrams, Kevin R. Coombes, Guy N. Brock
Simulation-derived best practices for clustering clinical data. J. Biomed. Informatics 118 (2021)
Caitlin E. Coombes, Zachary B. Abrams, Samantha Nakayiza, Guy N. Brock, Kevin R. Coombes
Umpire 2.0: Simulating realistic, mixed-type, clinical data for machine learning. F1000Research 9 (2020)
Lianbo Yu, Soledad Fernandez, Guy N. Brock
Power analysis for RNA-Seq differential expression studies using generalized linear mixed effects models. BMC Bioinform. 21 (1) (2020)
Jasmit S. Shah, Guy N. Brock, Jeremy Gaskins
BayesMetab: treatment of missing values in metabolomic studies using a Bayesian modeling approach. BMC Bioinform. (24) (2019)
Lianbo Yu, Jianying Zhang, Guy N. Brock, Soledad Fernandez
Fully moderated t-statistic in linear modeling of mixed effects for differential expression analysis. BMC Bioinform. (24) (2019)
Lianbo Yu, Soledad Fernandez, Guy N. Brock
Power analysis for RNA-Seq differential expression studies. BMC Bioinform. 18 (1) (2017)
Alexander C. Cambon, Kathy B. Baumgartner, Guy N. Brock, Nigel G. F. Cooper, Dongfeng Wu, Shesh N. Rai
Properties of adaptive clinical trial signature design in the presence of gene and gene-treatment interaction. Commun. Stat. Simul. Comput. 46 (10) (2017)
Jasmit S. Shah, Shesh N. Rai, Andrew P. DeFilippis, Bradford G. Hill, Aruni Bhatnagar, Guy N. Brock
Distribution based nearest neighbor imputation for truncated high dimensional data with applications to pre-clinical and clinical metabolomics studies. BMC Bioinform. 18 (1) (2017)
Michael E. Egger, John A. Myers, Forest W. Arnold, Leigh Ann Pass, Julio A. Ramirez, Guy N. Brock
Cost effectiveness of adherence to IDSA/ATS guidelines in elderly patients hospitalized for Community-Aquired Pneumonia. BMC Medical Informatics Decis. Mak. 16 (2016)
Jasmit S. Shah, Guy N. Brock, Shesh N. Rai
Metabolomics data analysis and missing value issues with application to infarcted mouse hearts. BMC Bioinform. 16 (S15) (2015)
Alexander C. Cambon, Kathy B. Baumgartner, Guy N. Brock, Nigel G. F. Cooper, Dongfeng Wu, Shesh N. Rai
Classification of clinical outcomes using high-throughput informatics: Part 2 - parametric method reviews. Model. Assist. Stat. Appl. 10 (2) (2015)
Alexander C. Cambon, Kathy B. Baumgartner, Guy N. Brock, Nigel G. F. Cooper, Dongfeng Wu, Shesh N. Rai
Classification of clinical outcomes using high-throughput informatics: Part 1 - nonparametric method reviews. Model. Assist. Stat. Appl. 10 (1) (2015)
Dake Yang, Rudolph S. Parrish, Guy N. Brock
Empirical evaluation of consistency and accuracy of methods to detect differentially expressed genes based on microarray data. Comput. Biol. Medicine 46 (2014)
Guy N. Brock, Partha Mukhopadhyay, Vasyl Pihur, Cynthia Webb, Robert M. Greene, M. Michele Pisano
MmPalateMiRNA, an R package compendium illustrating analysis of miRNA microarray data. Source Code Biol. Medicine 8 (2013)
Sunghee Oh, Dongwan D. Kang, Guy N. Brock, George C. Tseng
Biological impact of missing-value imputation on downstream analyses of gene expression profiles. Bioinform. 27 (1) (2011)
Guy N. Brock, William D. Beavis, Laura Salter Kubatko
Fuzzy logic and related methods as a screening tool for detecting gene regulatory networks. Inf. Fusion 10 (3) (2009)
Ping Xu, Guy N. Brock, Rudolph S. Parrish
Modified linear discriminant analysis approaches for classification of high-dimensional microarray data. Comput. Stat. Data Anal. 53 (5) (2009)
Guy N. Brock, John R. Shaffer, Richard E. Blakesley, Meredith J. Lotz, George C. Tseng
Which missing value imputation method to use in expression profiles: a comparative study and two selection schemes. BMC Bioinform. 9 (2008)