Graham T. Holt

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 5

Top Topics

Recursive Algorithm

Simulated Annealing

Protein Protein

Energy Landscape

Top Venues

PLoS Comput. Biol.

J. Comput. Biol.

J. Comput. Chem.

Publications

Siyu Wang, Stephanie M. Reeve, Graham T. Holt, Adegoke A. Ojewole, Marcel S. Frenkel, Pablo Gainza, Santosh Keshipeddy, Vance G. Fowler, Dennis L. Wright, Bruce Randall Donald
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus. PLoS Comput. Biol. 18 (2) (2022)
Jonathan D. Jou, Graham T. Holt, Anna U. Lowegard, Bruce Randall Donald
Minimization-Aware Recursive K*: A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape. J. Comput. Biol. 27 (4) (2020)
Anna U. Lowegard, Marcel S. Frenkel, Graham T. Holt, Jonathan D. Jou, Adegoke Ojewole, Bruce Randall Donald
Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD: KRas protein-protein interface. PLoS Comput. Biol. 16 (6) (2020)
Jonathan D. Jou, Graham T. Holt, Anna U. Lowegard, Bruce Randall Donald
Minimization-Aware Recursive K^* K ∗ ( MARK^* MARK ∗ ): A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape. RECOMB (2019)
Mark A. Hallen, Jeffrey W. Martin, Adegoke Ojewole, Jonathan D. Jou, Anna U. Lowegard, Marcel S. Frenkel, Pablo Gainza, Hunter M. Nisonoff, Aditya Mukund, Siyu Wang, Graham T. Holt, David Zhou, Elizabeth Dowd, Bruce Randall Donald
OSPREY 3.0: Open-source protein redesign for you, with powerful new features. J. Comput. Chem. 39 (30) (2018)