Christoph Lange

Publication Activity (10 Years)

Years Active: 2006-2024
Publications (10 Years): 9

Top Topics

Chronic Obstructive Pulmonary Disease

Outlier Detection

Cooperative Learning

Similarity Matrices

Top Venues

Briefings Bioinform.

Publications

Georg Hahn, Dmitry Prokopenko, Julian Hecker, Sharon Marie Lutz, Kristina Mullin, Leinal Sejour, Winston Hide, Ioannis Vlachos, Stacia Desantis, Rudolph E. Tanzi, Christoph Lange
Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data. Briefings Bioinform. 25 (4) (2024)
Georg Hahn, Sharon Marie Lutz, Julian Hecker, Dmitry Prokopenko, Michael H. Cho, Edwin K. Silverman, Scott T. Weiss, Christoph Lange
Fast computation of the eigensystem of genomic similarity matrices. BMC Bioinform. 25 (1) (2024)
Sanghun Lee, Georg Hahn, Julian Hecker, Sharon Marie Lutz, Kristina Mullin, Winston Hide, Lars Bertram, Dawn L. Demeo, Rudolph E. Tanzi, Christoph Lange, Dmitry Prokopenko
A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets. Briefings Bioinform. 24 (1) (2023)
Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Jonathan Abraham, Tanya Novak, Julian Hecker, Michael Cho, Surender Khurana, Lindsey R. Baden, Adrienne G. Randolph, Scott T. Weiss, Christoph Lange
Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest. BMC Bioinform. 23 (1) (2022)
Julian Hecker, F. William Townes, Priyadarshini Kachroo, Cecelia A. Laurie, Jessica Lasky-Su, John Ziniti, Michael H. Cho, Scott T. Weiss, Nan M. Laird, Christoph Lange
A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests. Bioinform. 36 (22-23) (2021)
Georg Hahn, Sharon Marie Lutz, Nilanjana Laha, Michael H. Cho, Edwin K. Silverman, Christoph Lange
A fast and efficient smoothing approach to Lasso regression and an application in statistical genetics: polygenic risk scores for chronic obstructive pulmonary disease (COPD). Stat. Comput. 31 (3) (2021)
Georg Hahn, Sharon Marie Lutz, Julian Hecker, Dmitry Prokopenko, Christoph Lange
Local and Global Stratification Analysis in Whole Genome Sequencing (WGS) Studies Using LocStra. ICCABS (2019)
Daniel Schlauch, Heide Loehlein Fier, Christoph Lange
Identification of genetic outliers due to sub-structure and cryptic relationships. Bioinform. 33 (13) (2017)
Dmitry Prokopenko, Julian Hecker, Edwin K. Silverman, Marcello Pagano, Markus M. Nöthen, Christian Dina, Christoph Lange, Heide Loehlein Fier
Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project. Bioinform. 32 (9) (2016)
Dandi Qiao, Michael H. Cho, Heide Loehlein Fier, Per S. Bakke, Amund Gulsvik, Edwin K. Silverman, Christoph Lange
On the simultaneous association analysis of large genomic regions: a massive multi-locus association test. Bioinform. 30 (2) (2014)
Sungkyoung Choi, Sungyoung Lee, Sven Cichon, Markus M. Nöthen, Christoph Lange, Taesung Park, Sungho Won
FARVAT: a family-based rare variant association test. Bioinform. 30 (22) (2014)
Heide Loehlein Fier, Sungho Won, Dmitry Prokopenko, Taofik AlChawa, Kerstin U. Ludwig, Rolf Fimmers, Edwin K. Silverman, Marcello Pagano, Elisabeth Mangold, Christoph Lange
'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate. Bioinform. 28 (23) (2012)
Dandi Qiao, Wai-Ki Yip, Christoph Lange
Handling the data management needs of high-throughput sequencing data: SpeedGene, a compression algorithm for the efficient storage of genetic data. BMC Bioinform. 13 (2012)
Wai-Ki Yip, Christoph Lange
Quantitative trait prediction based on genetic marker-array data, a simulation study. Bioinform. 27 (6) (2011)
Iuliana Ionita-Laza, Nan M. Laird, Benjamin A. Raby, Scott T. Weiss, Christoph Lange
On the frequency of copy number variants. Bioinform. 24 (20) (2008)
Thomas Hoffmann, Christoph Lange
BAT: a massive parallel implementation of PBAT for genome-wide association studies in R. Bioinform. 22 (24) (2006)