Antti Poso

Publication Activity (10 Years)

Years Active: 2001-2024
Publications (10 Years): 9

Top Topics

Matrix Factorization

Severe Acute Respiratory Syndrome

Convolutional Neural Networks

Virtual Screening

Top Venues

J. Chem. Inf. Model.

PLoS Comput. Biol.

Publications

Mateus Sá Magalhães Serafim, Thales Kronenberger, Rafael Eduardo Oliveira Rocha, Amanda Del Rio Abreu Rosa, Thaysa Lara Gonçalves Mello, Antti Poso, Rafaela Salgado Ferreira, Jonatas Santos Abrahão, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Vinicius Gonçalves Maltarollo
Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach. J. Chem. Inf. Model. 64 (2) (2024)
Toni Sivula, Laxman Yetukuri, Tuomo Kalliokoski, Heikki Käsnänen, Antti Poso, Ina Pöhner
Machine Learning-Boosted Docking Enables the Efficient Structure-Based Virtual Screening of Giga-Scale Enumerated Chemical Libraries. J. Chem. Inf. Model. 63 (18) (2023)
Vinicius Gonçalves Maltarollo, Ekaterina Shevchenko, Igor Daniel de Miranda Lima, Elio A. Cino, Glaucio Monteiro Ferreira, Antti Poso, Thales Kronenberger
Do Go Chasing Waterfalls: Enoyl Reductase (FabI) in Complex with Inhibitors Stabilizes the Tetrameric Structure and Opens Water Channels. J. Chem. Inf. Model. 62 (22) (2022)
Lucianna Helene Santos, Thales Kronenberger, Renata G. Almeida, Elany B. Silva, Rafael E. O. Rocha, Joyce C. Oliveira, Luiza V. Barreto, Danielle Skinner, Pavla Fajtová, Miriam A. Giardini, Brendon Woodworth, Conner Bardine, André L. Lourenço, Charles S. Craik, Antti Poso, Larissa M. Podust, James H. McKerrow, Jair L. Siqueira-Neto, Anthony J. O'Donoghue, Eufrânio N. da Silva Júnior, Rafaela Salgado Ferreira
of SARS-CoV-2. J. Chem. Inf. Model. 62 (24) (2022)
Milla Kurki, Antti Poso, Piia Bartos, Markus S. Miettinen
Structure of POPC Lipid Bilayers in OPLS3e Force Field. J. Chem. Inf. Model. 62 (24) (2022)
Prasanthi Medarametla, Thales Kronenberger, Tuomo Laitinen, Antti Poso
Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models. J. Chem. Inf. Model. 61 (3) (2021)
Karim Abbasi, Parvin Razzaghi, Antti Poso, Massoud Amanlou, Jahan B. Ghasemi, Ali Masoudi-Nejad
DeepCDA: deep cross-domain compound-protein affinity prediction through LSTM and convolutional neural networks. Bioinform. 36 (17) (2020)
Karim Abbasi, Antti Poso, Jahan B. Ghasemi, Massoud Amanlou, Ali Masoudi-Nejad
Deep Transferable Compound Representation across Domains and Tasks for Low Data Drug Discovery. J. Chem. Inf. Model. 59 (11) (2019)
Tatu Pantsar, Sami Rissanen, Daniel Dauch, Tuomo Laitinen, Ilpo Vattulainen, Antti Poso
Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling. PLoS Comput. Biol. 14 (9) (2018)
Suleiman A. Khan, Seppo Virtanen, Olli-P. Kallioniemi, Krister Wennerberg, Antti Poso, Samuel Kaski
Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis. Bioinform. 30 (17) (2014)
Muhammad Ammad-ud-din, Elisabeth Georgii, Mehmet Gönen, Tuomo Laitinen, Olli-P. Kallioniemi, Krister Wennerberg, Antti Poso, Samuel Kaski
Integrative and Personalized QSAR Analysis in Cancer by Kernelized Bayesian Matrix Factorization. J. Chem. Inf. Model. 54 (8) (2014)
Johanna Jyrkkärinne, Jenni Küblbeck, Juha Pulkkinen, Paavo Honkakoski, Reino Laatikainen, Antti Poso, Tuomo Laitinen
Molecular Dynamics Simulations for Human CAR Inverse Agonists. J. Chem. Inf. Model. 52 (2) (2012)
Suleiman A. Khan, Ali Faisal, John Mpindi, Juuso A. Parkkinen, Tuomo Kalliokoski, Antti Poso, Olli-P. Kallioniemi, Krister Wennerberg, Samuel Kaski
Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs. BMC Bioinform. 13 (2012)
Pekka Tiikkainen, Patrick Markt, Gerhard Wolber, Johannes Kirchmair, Simona Distinto, Antti Poso, Olli-P. Kallioniemi
Critical Comparison of Virtual Screening Methods against the MUV Data Set. J. Chem. Inf. Model. 49 (10) (2009)
Pekka Tiikkainen, Antti Poso, Olli-P. Kallioniemi
Comparison of structure fingerprint and molecular interaction field based methods in explaining biological similarity of small molecules in cell-based screens. J. Comput. Aided Mol. Des. 23 (4) (2009)
Tuomo Kalliokoski, Heikki S. Salo, Maija Lahtela-Kakkonen, Antti Poso
The Effect of Ligand-Based Tautomer and Protomer Prediction on Structure-Based Virtual Screening. J. Chem. Inf. Model. 49 (12) (2009)
Tuomo Kalliokoski, Toni Rönkkö, Antti Poso
FieldChopper, A New Tool for Automatic Model Generation and Virtual Screening Based on Molecular Fields. J. Chem. Inf. Model. 48 (6) (2008)
Tero Huhtiniemi, Carsten Wittekindt, Tuomo Laitinen, Jukka Leppänen, Antero Salminen, Antti Poso, Maija Lahtela-Kakkonen
Comparative and pharmacophore model for deacetylase SIRT1. J. Comput. Aided Mol. Des. 20 (9) (2006)
Toni Rönkkö, Anu J. Tervo, Jussi Parkkinen, Antti Poso
BRUTUS: Optimization of a grid-based similarity function for rigid-body molecular superposition. II. Description and characterization. J. Comput. Aided Mol. Des. 20 (4) (2006)
Anu J. Tervo, Tommi H. Nyrönen, Toni Rönkkö, Antti Poso
Comparing the Quality and Predictiveness between 3D QSAR Models Obtained from Manual and Automated Alignment. J. Chem. Inf. Model. 44 (3) (2004)
Anu J. Tervo, Tommi H. Nyrönen, Toni Rönkkö, Antti Poso
A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods. J. Comput. Aided Mol. Des. 17 (12) (2003)
Antti Poso, Jukka Gynther, Risto Juvonen
A comparative molecular field analysis of cytochrome P450 2A5 and 2A6 inhibitors. J. Comput. Aided Mol. Des. 15 (3) (2001)