Anthony R. Bradley

Publication Activity (10 Years)

Years Active: 2014-2023
Publications (10 Years): 14

Top Topics

Community Driven

Protein Data Bank

Top Venues

J. Chem. Inf. Model.

PLoS Comput. Biol.

Nat. Mac. Intell.

Publications

Maranga Mokaya, Fergus Imrie, Willem P. van Hoorn, Aleksandra Kalisz, Anthony R. Bradley, Charlotte M. Deane
Testing the limits of SMILES-based de novo molecular generation with curriculum and deep reinforcement learning. Nat. Mac. Intell. 5 (4) (2023)
Daniel J. Woodward, Anthony R. Bradley, Willem P. van Hoorn
Coverage Score: A Model Agnostic Method to Efficiently Explore Chemical Space. J. Chem. Inf. Model. 62 (18) (2022)
Mihaela D. Smilova, Peter R. Curran, Chris J. Radoux, Frank von Delft, Jason C. Cole, Anthony R. Bradley, Brian D. Marsden
Fragment Hotspot Mapping to Identify Selectivity-Determining Regions between Related Proteins. J. Chem. Inf. Model. 62 (2) (2022)
Chris J. Radoux, Francesca V. Vianello, Jake E. McGreig, Nikita Desai, Anthony R. Bradley
The druggable genome: Twenty years later. Frontiers Bioinform. 2 (2022)
Fergus Imrie, Anthony R. Bradley, Charlotte M. Deane
Generating property-matched decoy molecules using deep learning. Bioinform. 37 (15) (2021)
Peter R. Curran, Chris J. Radoux, Mihaela D. Smilova, Richard A. Sykes, Alicia P. Higueruelo, Anthony R. Bradley, Brian D. Marsden, David R. Spring, Tom L. Blundell, Andrew R. Leach, William R. Pitt, Jason C. Cole
Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design. J. Chem. Inf. Model. 60 (4) (2020)
Fergus Imrie, Anthony R. Bradley, Mihaela van der Schaar, Charlotte M. Deane
Deep Generative Models for 3D Linker Design. J. Chem. Inf. Model. 60 (4) (2020)
Aleix Lafita, Spencer Bliven, Andreas Prlic, Dmytro Guzenko, Peter W. Rose, Anthony R. Bradley, Paolo Pavan, Douglas Myers-Turnbull, Yana Valasatava, Michael L. Heuer, Matt Larson, Stephen K. Burley, Jose M. Duarte
BioJava 5: A community driven open-source bioinformatics library. PLoS Comput. Biol. 15 (2) (2019)
Fergus Imrie, Anthony R. Bradley, Mihaela van der Schaar, Charlotte M. Deane
Protein Family-Specific Models Using Deep Neural Networks and Transfer Learning Improve Virtual Screening and Highlight the Need for More Data. J. Chem. Inf. Model. 58 (11) (2018)
Alexander S. Rose, Anthony R. Bradley, Yana Valasatava, Jose M. Duarte, Andreas Prlic, Peter W. Rose
NGL viewer: web-based molecular graphics for large complexes. Bioinform. 34 (21) (2018)
Peter W. Rose, Andreas Prlic, Ali Altunkaya, Chunxiao Bi, Anthony R. Bradley, Cole H. Christie, Luigi Di Costanzo, Jose M. Duarte, Shuchismita Dutta, Zukang Feng, Rachel Kramer Green, David S. Goodsell, Brian P. Hudson, Tara Kalro, Robert Lowe, Ezra Peisach, Christopher Randle, Alexander S. Rose, Chenghua Shao, Yi-Ping Tao, Yana Valasatava, Maria Voigt, John D. Westbrook, Jesse Woo, Huanwang Yang, Jasmine Young, Christine Zardecki, Helen M. Berman, Stephen K. Burley
The RCSB protein data bank: integrative view of protein, gene and 3D structural information. Nucleic Acids Res. 45 (Database-Issue) (2017)
Anthony R. Bradley, Alexander S. Rose, Antonín Pavelka, Yana Valasatava, Jose M. Duarte, Andreas Prlic, Peter W. Rose
MMTF - An efficient file format for the transmission, visualization, and analysis of macromolecular structures. PLoS Comput. Biol. 13 (6) (2017)
Alexander S. Rose, Anthony R. Bradley, Yana Valasatava, Jose M. Duarte, Andreas Prlic, Peter W. Rose
Web-based molecular graphics for large complexes. Web3D (2016)
Anthony R. Bradley, Ian D. Wall, Frank von Delft, Darren V. S. Green, Charlotte M. Deane, Brian D. Marsden
WONKA: objective novel complex analysis for ensembles of protein-ligand structures. J. Comput. Aided Mol. Des. 29 (10) (2015)
Anthony R. Bradley, Ian D. Wall, Darren V. S. Green, Charlotte M. Deane, Brian D. Marsden
OOMMPPAA: A Tool To Aid Directed Synthesis by the Combined Analysis of Activity and Structural Data. J. Chem. Inf. Model. 54 (10) (2014)