Bacterial genomes lacking long-range correlations may not be modeled by low-order Markov chains: The role of mixing statistics and frame shift of neighboring genes.
Germinal CochoPedro MiramontesRicardo MansillaWentian LiPublished in: Comput. Biol. Chem. (2014)
Keyphrases
- markov chain
- low order
- escherichia coli
- markov models
- long range correlations
- transition probabilities
- markov model
- high order
- higher order
- long range
- confidence intervals
- sequenced genomes
- genomic sequences
- comparative genomics
- state space
- linear combination
- markov processes
- numerical solution
- probabilistic automata
- random walk
- gene expression
- microarray data
- power law
- gene expression data
- binding sites
- conditional random fields
- maximum entropy
- pairwise
- optimal solution