Identification of protein-ligand binding site using multi-clustering and Support Vector Machine.
Ginny Y. WongFrank Hung-Fat LeungSteve S. H. LingPublished in: IECON (2016)
Keyphrases
- virtual screening
- protein protein
- binding sites
- support vector machine
- drug discovery
- similarity searching
- computational methods
- protein protein interactions
- high throughput
- dna binding
- sequence alignment
- mass spectrometry
- protein sequences
- dna sequences
- gene expression
- predicting protein
- regulatory elements
- protein interaction
- protein function
- interaction networks
- drug design
- sequence data
- scoring function
- statistical significance
- protein structure
- protein families
- transcription factors
- transcription factor binding sites
- molecular biology
- motif discovery
- data points
- machine learning
- support vector
- high dimensionality
- similarity search
- high dimensional data
- amino acid sequences
- protein complexes
- gene ontology
- biological data
- microarray
- statistical analysis
- remote homology detection