A strategy to build and validate a prognostic biomarker model based on RT-qPCR gene expression and clinical covariates.
Maud TournoudAudrey LarueMarie-Angelique CazalisFabienne VenetAlexandre PachotGuillaume MonneretAlain LepapeJean-Baptiste VeyrierasPublished in: BMC Bioinform. (2015)
Keyphrases
- gene expression
- gene expression data
- dna microarray
- microarray
- microarray data
- clinical data
- differentially expressed genes
- gene regulation
- gene expression patterns
- gene expression profiles
- gene expression analysis
- biological processes
- regulatory networks
- high throughput
- regression model
- gene expression data sets
- gene expression data analysis
- drosophila melanogaster
- analysis of gene expression
- high dimensionality
- microarray datasets
- data sets
- colon cancer
- disease progression
- gene regulatory networks
- gene expression datasets
- gene selection
- logistic regression
- genomic data
- survival data
- functional genomics
- binding sites
- gene ontology
- reverse engineering
- patient groups
- data analysis
- cancer classification