Obtaining extremely large and accurate protein multiple sequence alignments from curated hierarchical alignments.
Andrew F. NeuwaldChristopher J. LanczyckiTheresa K. HodgesAron Marchler-BauerPublished in: Database J. Biol. Databases Curation (2020)
Keyphrases
- multiple sequence alignments
- protein sequences
- multiple sequence alignment
- pairwise
- multiple alignment
- protein protein interactions
- sequence alignment
- phylogenetic trees
- computational biology
- biological sequences
- biomedical literature
- protein structure prediction
- genetic algorithm
- protein structure
- high accuracy
- memory efficient
- secondary structure
- coarse grained
- graph theoretic
- amino acids
- data mining