A New Redundant Variable Pruning Approach - minor Latent Variable Perturbation-PLS Used for QSAR Studies on Anti-HIV Drugs.
Hong-Ping XieJian-Hui JiangHui CuiGuo-Li ShenRu-Qin YuPublished in: Comput. Chem. (2002)
Keyphrases
- latent variables
- drug discovery
- observed variables
- drug design
- probabilistic model
- hierarchical model
- random variables
- human immunodeficiency virus
- gaussian process
- hidden variables
- early stage
- real valued
- latent variable models
- topic models
- prior knowledge
- drug resistance
- artificial intelligence
- regression model
- feature selection
- latent structure
- feature extraction
- latent factors
- latent space
- search space
- scientific data
- probability distribution
- knowledge representation
- databases
- information extraction