An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis.
Niki KaragianniKsanthi KranidiotiNikolaos FikasMaria TsochatzidouPanagiotis ChouvardasMaria C. DenisGeorge KolliasChristoforos NikolaouPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- probabilistic model
- theoretical framework
- computational model
- formal model
- conceptual model
- high level
- generic model
- statistical analysis
- mathematical model
- similarity measure
- neural network
- theoretical foundation
- conceptual framework
- main contribution
- user defined
- distance measure
- empirical data
- modeling framework
- mathematical framework