Bioinformatics-driven discovery of silica nanoparticles induces apoptosis and renal damage via the unfolded protein response in NRK-52E cells and rat kidney.
Naimeng LiuMeng LiHuan PangTian TiantianXinyue LiYanchi SuMinghua JinHao WuChuyue QianMindan SunPublished in: Comput. Biol. Medicine (2024)
Keyphrases
- protein structure prediction
- drug design
- multiple sequence alignment
- data mining
- sequence analysis
- drug discovery
- protein sequences
- regulatory networks
- sequence databases
- protein structure
- phase contrast
- protein structure and function
- motif discovery
- computational biology
- living cells
- protein functional
- cell lines
- proteomic data
- biological entities
- discovery process
- knowledge discovery
- sequence data
- protein function
- visual stimuli
- protein function prediction
- phase contrast microscopy
- machine learning
- sequence alignment
- systems biology
- text mining
- molecular biology
- biological data
- visual cortex
- data analysis
- mass spectrometry
- medical data
- dna sequences
- protein protein interactions
- pattern discovery
- amino acids
- using artificial neural networks
- early detection
- biological sequences