A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control.
Yinming JiaoMartin WidschwendterAndrew E. TeschendorffPublished in: Bioinform. (2014)
Keyphrases
- gene expression
- gene expression data
- microarray
- high throughput
- genome wide
- microarray technology
- gene regulation
- expression patterns
- microarray data
- binding sites
- gene selection
- transcription factors
- colon cancer
- dna binding
- gene expression data analysis
- gene expression analysis
- gene expression profiles
- gene regulatory networks
- expression profiles
- regulatory networks
- analysis of gene expression
- systems biology
- gene expression data sets
- data sets
- cancer diagnosis
- biological processes
- human genome
- cancer classification
- high dimensionality
- gene expression patterns
- experimental conditions
- gene networks
- feature selection
- functional genomics
- biological systems
- dna microarray
- gene ontology
- gene function
- high dimensional data
- genomic data
- microarray data analysis
- dimensionality reduction
- nearest neighbor
- machine learning