Protein-protein and protein-nucleic acid binding residues important for common and rare sequence variants in human.
Jiajun QiuDmitrii NechaevBurkhard RostPublished in: BMC Bioinform. (2020)
Keyphrases
- protein protein
- protein protein interactions
- protein sequences
- computational methods
- binding sites
- protein structure
- predicting protein
- protein function
- protein interaction
- high throughput
- transcription factor binding sites
- interaction networks
- predicting protein protein interactions
- sequence analysis
- protein complexes
- protein structural
- drug design
- sequence alignment
- amino acids
- amino acid sequences
- transcription factors
- computational biology
- biological processes
- multiple sequence alignments
- computational approaches
- molecular biology
- gene expression
- network topology
- secondary structure
- microarray
- protein data bank
- high precision
- systems biology
- protein families
- biological data
- dna sequences
- computational tools
- protein interaction networks
- experimentally determined
- statistical methods
- protein interaction data
- sequence data
- protein folding
- mass spectrometry
- genomic data
- genome wide
- gene ontology
- functional modules