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Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement.

Hanlun JiangFu Kit SheongLizhe ZhuXin GaoJulie BernauerXuhui Huang
Published in: PLoS Comput. Biol. (2015)
Keyphrases
  • gene expression
  • computational models
  • computational methods
  • co occurrence
  • secondary structure
  • regulatory networks
  • statistical methods
  • structural information
  • genome wide
  • protein interaction
  • tertiary structure