Holo Protein Conformation Generation from Apo Structures by Ligand Binding Site Refinement.
Jinze ZhangHao LiXuejun ZhaoQilong WuSheng-You HuangPublished in: J. Chem. Inf. Model. (2022)
Keyphrases
- binding sites
- protein protein
- virtual screening
- dna binding
- sequence alignment
- gene expression
- protein structure
- transcription factors
- dna sequences
- sequence data
- experimentally determined
- transcription factor binding sites
- regulatory elements
- protein interaction
- statistical significance
- drug discovery
- motif discovery
- similarity searching
- computational methods
- protein families
- protein protein interactions
- protein function
- high throughput
- protein sequences
- microarray
- predicting protein
- amino acid sequences
- cis regulatory
- molecular biology
- secondary structure