DeepSite: protein-binding site predictor using 3D-convolutional neural networks.
José JiménezStefan DoerrGerard Martínez-RosellAlexander S. RoseGianni De FabritiisPublished in: Bioinform. (2017)
Keyphrases
- convolutional neural networks
- binding sites
- virtual screening
- dna binding
- protein protein
- sequence alignment
- regulatory elements
- protein interaction
- convolutional network
- dna sequences
- drug discovery
- gene expression
- sequence data
- transcription factor binding sites
- protein protein interactions
- transcription factors
- similarity searching
- protein families
- protein sequences
- predicting protein
- high throughput
- statistical significance
- motif discovery
- computational methods
- interaction networks
- cis regulatory
- protein function
- genome sequences
- biological sequences
- amino acid sequences
- regulatory networks
- machine learning
- scoring function
- amino acids
- protein structure
- protein complexes
- functional modules
- protein structure prediction
- gene expression levels
- early stage
- statistically significant
- microarray
- text mining