A Virtual Active Compound Produced from the Negative Image of a Ligand-binding Pocket, and its Application to in-silico Drug Screening.
Yoshifumi FukunishiSatoru KubotaChisato KanaiHaruki NakamuraPublished in: J. Comput. Aided Mol. Des. (2006)
Keyphrases
- image analysis
- input image
- image features
- drug discovery
- image retrieval
- image classification
- image collections
- template matching
- test images
- single image
- multiscale
- image representation
- image segmentation
- high resolution
- image data
- positive and negative
- image content
- image matching
- feature points
- drug design
- spatial information
- segmentation method
- natural images
- image quality
- region of interest
- image regions
- scale space
- pixel values
- image pixels
- segmentation algorithm