Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach.
Lei DuKefei LiuXiaohui YaoShannon L. RisacherJunwei HanAndrew J. SaykinLei GuoLi ShenPublished in: Medical Image Anal. (2020)
Keyphrases
- brain imaging
- genome wide association studies
- genetic variation
- complex diseases
- human brain
- genome wide
- canonical correlation analysis
- human genome
- high throughput
- brain images
- image analysis
- biological knowledge
- single nucleotide polymorphisms
- factor analysis
- functional magnetic resonance imaging
- dna sequences
- pattern recognition
- brain regions
- gene expression
- least squares