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Binding-affinity predictions of HSP90 in the D3R Grand Challenge 2015 with docking, MM/GBSA, QM/MM, and free-energy simulations.

Majda Misini IgnjatovicOctav CaldararuGeng DongCamila Muñoz-GutiérrezFrancisco Adasme-CarreñoUlf Ryde
Published in: J. Comput. Aided Mol. Des. (2016)
Keyphrases
  • grand challenge
  • free energy
  • autonomous driving
  • posterior distribution
  • three dimensional
  • image sequences
  • prior knowledge
  • graphical models
  • belief propagation
  • fixed point
  • probability density function