Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model.
Andrew F. NeuwaldJun S. LiuPublished in: BMC Bioinform. (2004)
Keyphrases
- monte carlo
- hidden markov models
- protein sequences
- biological sequences
- multiple alignment
- multiple sequence alignment
- structural motifs
- computational biology
- rna sequences
- sequence alignment
- motif finding
- protein structure
- markov chain
- secondary structure
- motif discovery
- genome sequences
- sequence databases
- amino acids
- molecular biology
- particle filter
- conditional random fields
- biological data
- protein families
- dna sequences
- kernel methods