Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data.
Ketevan ChkhaidzeTimon HeideBenjamin WernerMarc J. WilliamsWeini HuangGiulio CaravagnaTrevor A. GrahamAndrea SottorivaPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- genomic data
- clonal selection
- gene expression profiles
- cancer diagnosis
- artificial immune system
- high throughput
- gene expression data
- biological data
- protein protein interactions
- breast cancer
- clonal selection algorithm
- gene expression
- gene ontology
- data mining techniques
- gene selection
- high dimensionality
- data mining
- feature space
- similarity measure