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Experimentally validated modeling of dynamic drug-hERG channel interactions reproducing the binding mechanisms and its importance in action potential duration.

Fernando EscobarSoren FriisNouran AdlyNina BrinkwirthJulio Gomis-TenaJavier SaizDan A. KlaerkeSonja Stoelzle-FeixLucía Romero
Published in: Comput. Methods Programs Biomed. (2024)
Keyphrases
  • experimentally validated
  • multi channel
  • dynamically evolving
  • dynamic environments
  • pharmaceutical industry
  • action selection